Veolia Water Technologies & Solutions

Sievers Eclipse*

simplified, automated testing

The Sievers Eclipse Bacterial Endotoxins Testing (BET) Platform uses microfluidic liquid handling and the latest in compliant software to simplify and automate your endotoxin testing program. Automation of BET is achieved using a compact benchtop platform - finally making it easy to run fully compliant endotoxin assays without difficult setup or complex robotics. With the Sievers Eclipse, QC labs can:

  • Experience easy, automated endotoxin testing that any analyst can perform. Minimal training is needed to run consistent, accurate, and compliant assays
  • Meet all requirements of the harmonized pharmacopoeia: USP <85>, EP 2.6.14 and JP 4.01
  • Ensure compliance with 21 CFR Part 11 and Data Integrity guidelines
  • Decrease assay setup time by up to 85% with <30 pipetting steps
  • Leverage microfluidics to minimize hands-on time, operator-to-operator variability, and retests
  • Reduce Limulus Amebocyte Lysate (LAL) reagent use up to 90%, decreasing demand on natural resources
  • Automate standard curves, positive product controls (PPCs), and mixing without the use of robotics
  • Achieve automation without the need for complex equipment and maintenance

compliant. consistent. conscious

La plateforme Eclipse permet l'automatisation et la précision des procédures de tests BET sans sacrifier la conformité, la réaction biochimique ou l'empreinte au laboratoire. With reduced LAL reagent use and 21 CFR Part 11 compliant software, the Sievers Eclipse platform delivers a fully compliant BET assay that the global horseshoe crab (HSC) population can sustain. From supply chain and storage to validation, routine testing, and sign-off, the Eclipse maximizes efficiency and streamlines product release.

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Ressources

Tests simplifiés des endotoxines, de l'inventaire à la libération des lots

This infographic provides a summary of the areas within a pharmaceutical manufacturing facility which can benefit from the Sievers Eclipse Bacterial Endotoxins Testing (BET) Platform. The Sievers Eclipse platform uses microfluidic automation and the latest in compliant software to simplify each step of an endotoxin testing program, from supply chain and storage to validation, routine testing, and sign off.

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Comment fonctionnent les différentes plateformes de test des endotoxines : un résumé des systèmes de test cinétique chromogène

Cette infographie compare le fonctionnement de différentes plateformes de test d'endotoxines et fournit un résumé des systèmes de test chromogène cinétique, y compris la plateforme de test d'endotoxines bactériennes (TEB) Eclipse de Sievers. The following aspects are compared between platforms: hands-on time, LAL usage, throughput, footprint, technology, software, standard curve automation, and validation considerations.

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