Centre de ressources Sievers

Comment les tests de validation du nettoyage en laboratoire se comparent-ils à la validation du nettoyage en ligne ou sur site ?

rylee.lay@veolia.com — Wed, 23 Apr 2025 17:05:04 +0000

How Does Cleaning Validation Testing in the Lab Compare to Online or At-line Cleaning Validation? rylee.lay@veolia.com Wed, 04/23/2025 - 13:05

April 23, 2025

Cleaning validation is an integral component to cGMP manufacturing in the pharmaceutical industry to ensure safety and purity of products. Total organic carbon (TOC) and conductivity are important quality metrics used in cleaning validation to understand and control the cleanliness of equipment, and advances in technology now allow monitoring to be faster and more reliable than ever. With process analytical technology (PAT) and automation, users have the opportunity to build quality and efficiency into their cleaning programs and decrease human interaction, out-of-specification (OOS) investigations, and equipment downtime.

The three common deployments of TOC technology are laboratory, at-line, and online analysis. When choosing which deployment will best support the overall validation strategy and sampling methods, consider the following to ensure you get the most out of the technology.

Laboratory Analysis (TOC testing performed offline, typically in the QC laboratory):

Benchtop TOC analyzers and software are available that allow you to stack protocols, run system protocols, run large volumes of samples at a time, manage data, and electronically sign and export data. With laboratory analysis, it is inevitable that grab samples must be taken from equipment or purified water points of use.

At-line Analysis (TOC testing performed on the manufacturing floor next to equipment being cleaned):

At-line deployment uses a portable TOC analyzer located directly next to the process to be monitored, reducing downtime. Il peut fournir des gains d’efficacité pour la bonne application par rapport à l’analyse en laboratoire. La surveillance sur la ligne évite le flux de travail qualité et génère des données dans les minutes qui suivent le prélèvement de l’échantillon. This can significantly reduce the amount of time that manufacturing equipment sits idle.

Online Analysis (TOC testing performed from final rise of cleaning cycle):

Online TOC and conductivity testing allows you to go from days to minutes for equipment release time. La validation du nettoyage en ligne avec les analyseurs de COT Sievers permet de fournir en temps réel des données validées avec le plus haut degré d’intégrité des données, de compréhension du processus et de contrôle de ce dernier. Avec des gains d’efficacité et des rapports transparents, vous obtenez une évaluation complète de la propreté avec moins de risques d’erreur. Online analysis allows you to assess the real-time rinse down profile of your process, and leverage 3 key quality metrics for process understanding - inorganic carbon, TOC, and conductivity.

Whether deploying laboratory, at-line, or online TOC analysis for cleaning validation or water testing, consider your goals around efficiency, analytical performance, and data integrity. Les instruments d'analyse qui peuvent fournir une exactitude, une précision et une intégrité des données élevées tout en vous offrant la possibilité de vous faire gagner du temps seront les plus précieux pour vos programmes de surveillance. Contact a Sievers expert to learn more about what method of analysis is right for you.

Sievers Resource Center Industry

Life Sciences

Sievers Resource Center Type

FAQs

Veolia Water Technologies élargit ses solutions mobiles de traitement de l'eau au Brésil, faisant progresser les solutions durables relatives à l'eau pour les municipalités et les industries principales

rylee.lay@veolia.com — Mon, 14 Apr 2025 21:20:51 +0000

Veolia Water Technologies expands mobile water treatment capabilities in Brazil, advancing sustainable water solutions for municipalities and key industries rylee.lay@veolia.com Mon, 04/14/2025 - 17:20

April 15, 2025

Latin America

Veolia has established a new dedicated Service Center in Cajamar to enhance its mobile water treatment fleet - the largest in Brazil - optimizing logistics and accelerating sustainable water solutions for industrial and municipal sectors.
The company's specialized production plant in Sorocaba now focuses on advanced membrane technology, reinforcing Veolia's position as world leader in water technologies.
This strategic reorganization aligns with Veolia's GreenUp strategic program, driving innovation in water treatment and resource management to address critical global challenges.

Veolia Water Technologies, the world leader in water technologies, announces the opening of a new Mobile Water Service Center in Cajamar, São Paulo, Brazil. This state-of-the-art facility is dedicated to maintaining and managing Veolia's extensive fleet of mobile water treatment units - the largest in the country - marking a significant step forward in providing sustainable water solutions to strategic industries across Latin America.

The new Mobile Water Service Center strengthens Veolia's ability to deploy rapid, flexible and sustainable water solutions, boosting resilience for industrial and municipal clients. These mobile units serve a wide range of applications, from demineralized water production to water clarification, wastewater treatment and water reuse. This expanded service offering ensures uninterrupted water availability, safeguards business continuity and advances water circularity, providing clients with a robust shield against water-related challenges.

Complementing this expansion, Veolia's plant in Sorocaba (SP) now specializes in the production of cutting-edge water treatment equipment featuring advanced membrane technology. Drawing on Veolia's 30 years of pioneering membrane expertise, the plant serves as a cornerstone for high quality water treatment and wastewater regeneration in both industrial and municipal applications. This strategic reorganization enables Veolia to better serve municipalities and key industries by offering innovative solutions that promote efficient water resource management.

Mauro Cruz, who heads Water Technologies activities for Veolia in Latin America, stated: "Our new Mobile Water Service Center in Cajamar significantly enhances our ability to serve our customers with greater efficiency and quality. By expanding our mobile fleet capabilities, we're actively addressing water scarcity and quality issues that challenge industries and municipalities across Latin America. This strategic expansion, aligned with Veolia's global GreenUp program, positions us as a key partner in building a more resilient, sustainable water future, accelerating ecological transformation in the region and beyond."

ABOUT VEOLIA

Veolia group aims to become the benchmark company for ecological transformation. Present on five continents with 215,000 employees, the Group designs and deploys useful, practical solutions for the management of water, waste and energy that are contributing to a radical turnaround of the current situation. Through its three complementary activities, Veolia helps to develop access to resources, to preserve available resources and to renew them. In 2024, the Veolia group provided 111 million inhabitants with drinking water and 98 million with sanitation, produced 42 million megawatt hours of energy and treated 65 million tonnes of waste. Veolia Environnement (Paris Euronext: VIE) achieved consolidated revenue of 44.7 billion euros in 2024. www.veolia.com

ABOUT VEOLIA WATER TECHNOLOGIES

As the global water technology experts of Veolia, we deliver on both performance and sustainability without compromise. We provide you with peace of mind knowing your business and communities are safeguarded, efficient and resilient. Together we protect, preserve and reuse resources, tackling today's environmental challenges while creating the water treatment and process solutions of tomorrow. www.watertechnologies.com

CONTACTS

VEOLIA WATER TECH LATAM
Diego Fuentes
Tel.+55 (11) 971 36 57 52
diego.fuentes1@veolia.com

VEOLIA WATER TECH GLOBAL MEDIA RELATIONS
Manon Painchaud
Tel.+1 418 573 2735
manon.painchaud@veolia.com

Bonnes pratiques pour les tests de la conductivité de l'eau à usage pharmaceutique

rylee.lay@veolia.com — Mon, 07 Apr 2025 04:20:21 +0000

Best Practices for Pharmaceutical Water Conductivity Testing rylee.lay@veolia.com Mon, 04/07/2025 - 00:20

April 7, 2025

Understanding USP <645> Water Conductivity Testing Requirements

Sievers instruments, software, consumables, services, and expertise center around ensuring compliance for requirements for drug quality and the quality of water for pharmaceutical and analytical purposes, such as USP <645> Water Conductivity. Selon l'USP et d'autres référentiels harmonisés, la conductivité est une mesure de qualité importante qui doit être contrôlée pour assurer la qualité du produit et la sécurité du patient. Il s’agit de l’un des deux principaux tests de limite chimique (l’autre est l’USP <643> carbone organique total) utilisé pour confirmer le contrôle de la contamination dans le système de purification de l’eau. La conductivité peut également être utilisée en complément des tests de COT comme outil de contrôle de processus en temps réel pour la purification de l’eau et d’autres procédés de production. Consisting of different stages of analysis, conductivity testing of Purified Water and Water for Injection allows pharmaceutical companies to maintain and treat their water to confirm purity and suitability for pharmaceutical applications.

Conductivity Methods

Traditional conductivity methods using a meter and probe, while compliant, introduce integrity and efficiency weaknesses. L’analyse manuelle d’un échantillon l’expose au CO2 atmosphérique, ce qui peut entraîner une surdéclaration par rapport aux limites de niveau 1. Une autre méthode de mesure de la conductivité consiste à utiliser un analyseur avec une cellule de conductivité en ligne. Cette possibilité offre des gains d’efficacité et d’intégrité des échantillons par rapport aux autres méthodes de laboratoire. By automating Stage 1 conductivity, labs realize great efficiency gains while improving sample handling and data management and reducing opportunity for error.

Conductivity Verification

USP and other harmonized compendia require conductivity cell constant verification to be performed regardless of the method or instrument used (meter, probe, or analyzer). L’USP <645> énonce l’exigence de vérification, mais ne prescrit pas la fréquence ou la concentration. Many pharmaceutical companies choose to go beyond only the cell constant verification and perform method suitability checks with other concentrations and acceptance criteria determined by process capabilities,

Best Practices for Conductivity Testing

Using an analyzer with an in-line conductivity cell and TOC testing capabilities, such as the Sievers M9 TOC Analyzer, is ideal for Stage 1 conductivity testing. Together with Dual Use Conductivity and TOC - DUCT - vials, this measurement approach provides accuracy and efficiency for water measurements.

For pharmaceutical manufacturers, the most desirable state for compliance with USP <645> is to meet the requirements of Stage 1 conductivity testing. Il s'agit de la méthode la plus simple à exécuter, qui nécessite le moins de temps par échantillon. Automating the testing for USP <645> offers significant time savings as well as increased data integrity and security.

Sievers Resource Center Industry

Life Sciences

Sievers Resource Center Type

Tips & Tricks

Modifications de l’USP <643> de carbone organique total dans l’eau stérile

rylee.lay@veolia.com — Mon, 07 Apr 2025 04:05:36 +0000

Changes to USP <643> Total Organic Carbon in Sterile Water rylee.lay@veolia.com Mon, 04/07/2025 - 00:05

April 2, 2025

Testing the quality of pharmaceutical grade water is not only important for drug product quality and safety, but it is strictly enforced by regulatory bodies around the world such as the United States Pharmacopeia (USP). L'USP <643> a été amendée en mai 2021 pour exiger que l'eau stérile conditionnée ait des limites de COT et des concentrations d'adéquation du système dépendant du volume du récipient. TOC is an important quality attribute that contributes to understanding water quality before use in critical applications.

TOC Limits for Pharmaceutical Water - What Changed?

Previously, sterile water had a standardized limit and system suitability concentration of 8 ppm. Cette concentration était appliquée quelle que soit la taille du récipient. Avec les modifications de 2021 apportées à l’USP <643>, la limite de COT est passée d’une valeur définie de 8,0 mg/L C (8 ppm) à une limite variable déterminée par le volume du contenant. This testing procedure changed from a pass/fail limit test to a staged testing procedure.

Why Were the Changes Implemented?

If Bulk Water Meets TOC Conductivity Requirements, Why Would It Have to Be Tested After Packaging? Lorsque l’eau est emballée, il y a un risque que des impuretés organiques s’infiltrent de l’emballage dans l’eau. Des supports de taille différente pour les contenants peuvent permettre de remédier aux différences de rapport surface/volume. Par exemple, les contenants de faible volume qui se situent dans la fourchette de récipient de <5 ml ont un rapport surface/volume plus élevé que celui des contenants plus grands, ce qui augmente les possibilités de lixiviation des impuretés organiques. Although bulk waters may have met acceptance criteria of USP <643>, this does not represent water quality following manufacturing of packaged water.

Is the Methodology or Technology Required Different?

The methodology for analyzing total organic carbon has not changed. All technologies must be able to discriminate between CO2 generated from oxidation and inorganic carbon that can be present in water samples prior to analysis.

Are New Standards Needed?

Are There New System Suitability Requirements for Sterile Water TOC Analysis? Les révisions de l’USP pour l’eau conditionnée stérile exigent que les critères d’adéquation et d’acceptation du système dépendent des volumes des conteneurs. La benzoquinone et le saccharose sont toujours les composés requis ; cependant, les concentrations ont changé pour refléter la taille du volume du contenant. Compte tenu de ces changements, il est important d’examiner la technologie et les procédures pour s’assurer que les tests de COT sont conformes aux attentes réglementaires. Le Sievers M9 peut pleinement prendre en charge ces changements grâce à sa plage d’analyse, son exactitude, sa précision et l’intégrité des données. En outre, Sievers a défini les configurations de protocole recommandées pour permettre aux utilisateurs d'effectuer facilement des analyses. More details are provided in this article here.

Sievers Resource Center Industry

Life Sciences

Sievers Resource Center Type

FAQs

Sept raisons pour lesquelles les techniciens du contrôle qualité passent à Eclipse pour réaliser des tests d'endotoxines bactériennes plus faciles

rylee.lay@veolia.com — Wed, 26 Mar 2025 16:56:33 +0000

Seven Reasons QC Analysts Are Switching to the Eclipse For Easier BET rylee.lay@veolia.com Wed, 03/26/2025 - 12:56

March 24, 2025

Simplified Quality Control (QC) testing is a must in pharmaceutical and medical device manufacturing today. The Sievers Eclipse BET Platform not only offers simplification, but it also offers compliance and a significant reduction in the use of Limulus Amebocyte Lysate (LAL) and other resources. Learn why analysts all over the world are switching to the Eclipse and reaping the benefits of improved QC testing and simplification using centripetal microfluidics for BET.

The Sievers Eclipse is user friendly and fully compliant with all compendia including requirements of USP <85>, EP 2.6.14, and JP 4.01.
The Sievers Eclipse runs a minimum 3-point standard curve in at least duplicate using standardized endotoxin . Pre-loaded standards and PPCs save time and reduce pipetting Negative controls are in at least duplicate
The Eclipse reduces opportunity for contamination and errors using an enclosed system, automation, and significantly fewer pipetting steps.
The Sievers Eclipse minimizes LAL usage by up to 90% compared to traditional assays.
You can increase and improve operational efficiency with the ability to run multiple plates in just a few hours and run 63 samples with just one (1) vial of LAL reagent.
The Sievers Eclipse enterprise software is fully compliant with 21 CFR Part 11 and ALCOA+ data integrity guidelines. And it's easy to use, includes assay-specific audit trails, and offers electronic signature for remote sign off.
Training and validation are easy and streamlined - validation can be completed within a few days, and you can train an analyst in just a few hours.

The Sievers Eclipse BET platform can greatly improve the efficiency of your BET processes. Simplify Your BET testing today.

Author:

Author: Meg Provenzano Life Sciences Product Manager of Bio-Detection, Veolia Water Technologies & Solutions, Sievers Instruments

She has over 10 years of experience in the bacterial endotoxin testing industry and has held several positions in Quality Control, Technical Support, and Product Management. Elle est attentive aux besoins des clients et aime résoudre les problèmes sur le terrain, qu’il s’agisse de questions techniques, d’aide à l’analyse ou de logiciels. Meg holds a B.S. in Marine Science and Biology from Coastal Carolina University where she focused on Bottlenose Dolphin population research.

Sievers Resource Center Industry

Life Sciences

Sievers Resource Center Type

Tips & Tricks

Veolia et le SIAAP inaugurent une nouvelle unité de décantation primaire pour l’épuration des eaux usées, alliant performance industrielle et préservation de l’environnement sur le site de Seine Aval

rylee.lay@veolia.com — Mon, 24 Mar 2025 19:23:08 +0000

Veolia and SIAAP inaugurate a new primary settling unit for wastewater treatment, combining industrial performance and environmental preservation at the Seine Aval site rylee.lay@veolia.com Mon, 03/24/2025 - 15:23

March 18, 2025

Europe

As SIAAP's historic facility and Europe's largest treatment site, Seine Aval serves a crucial role in the Paris region's sanitation, treating wastewater from 6 million inhabitants daily.
The site achieves a significant milestone in its modernization with the inauguration of a new primary settling unit, delivering more agile, efficient and energy-saving wastewater treatment while reducing nuisances.
Constructed by Veolia, this new facility can treat up to 34 m3/s of wastewater - equivalent to more than 50 Olympic swimming pools - making it Europe's largest treatment capacity installation.

SIAAP (Greater Paris Interdepartmental Sanitation Authority) and Veolia, global leader in ecological transformation, inaugurated a new primary settling unit at the Seine Aval plant (78) on Tuesday, March 18 2025. The ceremony was attended by Estelle Brachlianoff, Veolia Group CEO, François-Marie Didier, SIAAP President, and Anne Le Guennec, Veolia Senior Executive Vice President of Worldwide Water Technologies, along with elected officials and state representatives.

In the Paris region, efficient wastewater treatment is particularly critical due to the high population density and substantial volumes of wastewater requiring treatment. With millions of inhabitants, treatment plants must operate efficiently to prevent system saturation and minimize pollution in waterways such as the Seine and Marne rivers. Additionally, since the region frequently experiences heavy rainfall, the primary settling system is designed to handle flow variations by treating up to 34 m3/s - equivalent to more than 50 Olympic pools per hour. This helps preserve water quality and ensure sustainable sanitation for the region's residents.

As part of commitments made to comply with European water directives, the new installation complements existing systems and enables better wastewater treatment by eliminating fine particles, reducing carbon and phosphorus content, and optimizing the water purification process.

This inauguration marks a significant milestone in the extensive modernization project of Seine Aval, initiated in 2009. As SIAAP's historic facility and Europe's largest treatment site, it plays a vital role in the region's sanitation, treating wastewater from 6 million inhabitants daily.

A new installation with exceptional performance

Primary settling represents a critical phase in wastewater treatment. Following the pretreatment stage, it focuses on removing suspended matter and phosphorus ahead of biological treatment. This essential step conditions the water for subsequent purification processes.

The new primary settling unit, which complements existing installations, stands as Europe's largest such facility and marks a significant breakthrough in wastewater treatment for the Paris region. Completed after three years of work, the project required an investment of 511 million euros, with 498 million allocated to the Veolia-led consortium.

It relies on several major innovations to:

Better distribute effluents based on flow rates and pollution loads.
Improve the quality of water discharged into the Seine river through advanced technologies including lamellar settlers that remove ultra-fine waste particles and treat dissolved phosphorus and carbon pollution.
Reduce odor nuisances for residents through fully covered installations equipped with an odor treatment system.

A model of energy and environmental efficiency

The new primary settling reduces its environmental impact while maximizing its performance:

A heat recovery system has been installed on treated water (Energido™).
The settlers benefit from an elaborate washing system ensuring better sludge quality enabling optimized biogas production.
Energy and reagent consumption (Predifloc™) is optimized through predictive and real-time control using latest-generation digital tools.

Furthermore, biodiversity protection is enhanced through preservation measures for local fauna and flora.

This new primary settling unit demonstrates that industrial performance, environmental protection and residents' quality of life can be successfully harmonized, paving the way for a new generation of water treatment facilities.

"Since 2019, the Seine Aval site, Europe's largest treatment plant, has undergone continuous modernization. SIAAP's primary focus remains improving industrial safety and treatment performance across its facilities. The new primary settling unit, built by Veolia and its partners, fully achieves these goals. It will provide SIAAP with a new facility that concentrates technologies perfectly suited to the challenges of its activity and mission in service of water and the environment," states François-Marie Didier, SIAAP President.

"We are very proud to inaugurate today, alongside SIAAP, this new primary settling unit at the Seine-Aval site," adds Estelle Brachlianoff, Veolia CEO. "Through this landmark project, Veolia reaffirms its commitment to operational excellence and innovation serving territories and their inhabitants. This partnership, leveraging our know-how and expertise, not only meets growing regulatory requirements but also the legitimate expectations of elected officials and residents regarding environmental performance. It perfectly embodies the vision we carry within our GreenUp strategic program: bringing cutting-edge solutions to address current and future societal challenges."

ABOUT VEOLIA

PetStar accélère son processus de neutralité de l'eau avec Veolia au Mexique, marquant ainsi 30 ans de leadership environnemental

rylee.lay@veolia.com — Mon, 24 Mar 2025 18:39:23 +0000

PetStar speeds up water neutrality journey with Veolia in Mexico, marking 30 years of environmental leadership rylee.lay@veolia.com Mon, 03/24/2025 - 14:39

March 24, 2025

Latin America

Veolia enables PetStar to recover 370 cubic meters of water daily through advanced wastewater reuse technologies - equivalent to half the daily water consumption of the plant's surrounding community.
This strategic partnership combines PetStar's circular economy leadership (processing 5.5 billion bottles annually) with Veolia's cutting-edge water technologies, demonstrating how industry leaders can drive both business growth and environmental protection through water resource conservation.

Veolia Water Technologies, world leader in water technologies, has implemented cutting-edge wastewater reuse technologies for PetStar, a wholly Mexican company recognized globally for its leadership in food-grade PET collection and recycling. These technologies enable the world's largest food-grade PET recycling facility to advance towards its water neutrality goals. This partnership marks a significant milestone in PetStar's three decades of resource conservation stewardship.

As a global leader in PET bottle recycling, PetStar processes 5.5 billion bottles annually, producing high-quality food-grade recycled resin that meets the highest quality standards. The company's commitment to a circular economy now extends beyond plastic recycling to water conservation and regeneration, having found in Veolia an ally to advance its water neutrality goal. The advanced water reuse project commissioned by Veolia in 2025 enables PetStar to treat and reuse up to 550 cubic meters of wastewater per day from its recycling process, meeting quality standards set by NOM-001-SEMARNAT-2021 and significantly reducing underground water usage.

Founded in 1995, PetStar has served as a circular economy business model benchmark, addressing global challenges such as climate change, biodiversity loss, waste and plastic pollution through a human rights lens, aligned with the SDGs and Agenda 2030. Since 2011, the company has operated with the support of Arca Continental as its main shareholder, alongside Coca-Cola Mexico, Bepensa Bebidas, Corporación del Fuerte, Grupo RICA, Grupo Embotellador Nayar and Embotelladora de Colima, all part of Coca-Cola Bottling.

"PetStar's commitment to sustainability has remained unwavering over 30 years, driving our process innovation to generate value for our shareholders, create positive social impact and promote resource regeneration, including water," said Carlos Mendieta, Director of Public Affairs, Communications and Sustainability at PetStar Mexico. "Partnering with Veolia allows us to go beyond PET. By recycling our processed water we are taking another step towards a circular economy, achieving our water neutral commitments through water conservation, nature regeneration at the Nevado de Toluca, and rainwater harvesting from our green roofs - the four key pillars of our water footprint management."

The novel wastewater reuse solutions implemented by Veolia include advanced proprietary technologies such as Densator™ for rapid sedimentation, ZeeWeed™ Membrane Bioreactor (MBR), PROflex™ reverse osmosis process, and Aquaray™ UV disinfection technology. The reuse of process water thanks to the solution implemented by Veolia allows PetStar to reduce its dependence on natural resources, recovering 370 cubic meters of water daily - equivalent to half the daily consumption of the surrounding San Cayetano Morelos community.

Mauro Cruz, who heads Water Technologies activities for Veolia in Latin America, stated: "For Veolia, partnering with visionary companies like PetStar exemplifies the commitments we have made through our GreenUp strategic program. As their trusted partner in achieving water neutrality, we are demonstrating how the use of innovative technology can harmonize business growth with resource conservation. This collaboration proves that when industry leaders join forces, we can create sustainable solutions that protect our planet's precious water resources while driving operational excellence."

ABOUT VEOLIA

ABOUT VEOLIA WATER TECHNOLOGIES

CONTACTS

VEOLIA WATER TECH LATAM
Diego Fuentes
Tel.+55 (11) 971 36 57 52
diego.fuentes1@veolia.com

VEOLIA WATER TECH GLOBAL MEDIA RELATIONS
Manon Painchaud
Tel.+1 418 573 2735
manon.painchaud@veolia.com

Veolia encourage l’entrepreneuriat : Graines de Boss se lance en Belgique et en Espagne, les start-ups sont invitées à postuler pour faire leur entrée sur le marché français

rylee.lay@veolia.com — Wed, 26 Feb 2025 16:27:05 +0000

Veolia champions entrepreneurship: Graines de Boss launches in Belgium and Spain, start-ups invited to apply for a gateway to the French market rylee.lay@veolia.com Wed, 02/26/2025 - 11:27

February 26, 2025

Europe

Applications are now open for the Belgian and Spanish editions of the contest with one laureate to be selected in each country.
Winning start-ups will pitch to over 200 top-level mentors in Paris in June 2025.
The event aims to facilitate commercial contracts between Belgian and Spanish start-ups and French companies, with a focus on driving ecological transformation and sustainable innovation across Europe.

Graines de Boss, the prestigious entrepreneurship competition established in France in 2004, has expanded its reach to Belgium and Spain, opening new horizons for entrepreneurial minds in these countries. These nations were selected due to their close commercial ties with France, with a long-term vision of extending the competition to other European countries. GDB LINK, the global arm of Graines de Boss, was created to foster local economic development outside of France's borders, with a focus on urban revitalization, environmental services and sustainability, particularly in areas such as water and wastewater treatment.

Veolia, a global leader in ecological transformation and a long-standing partner of Graines de Boss, has been instrumental in this expansion. The company has historically been closely linked with Graines de Boss and is actively participating in its international growth, particularly to engage with European start-ups in the field of environmental solutions and services. Reflecting its core mission and values, the company's executives have served as mentors and jury members, as well as providing financing for winning projects through GDB Capital. Veolia Water Technologies group is now sponsoring the competition's growth through GDB LINK. This partnership exemplifies Veolia's dedication to nurturing entrepreneurship both in France and internationally, and to support start-ups with high potential for positive environmental impact.

The Belgian and Spanish contests, launched in October 2024 during an event at the French Ministry of Economy in Paris, are now accepting applications. The two winning start-ups, one from each country, will have the extraordinary opportunity to pitch their ideas in Paris on 24 June 2025, before an audience of over 200 mentors comprising top-level managers from leading French corporations. This event aims to facilitate commercial contracts between these international start-ups and French companies, thereby strengthening European entrepreneurial bonds.

Fabrice Delon, Founding CEO of Graines de Boss, shared: "We are grateful to Veolia for their crucial support in expanding our international acceleration program to include Spanish and Belgian start-ups alongside French talents. For 21 years, Graines de Boss has showcased France's top innovations. Now, with Veolia's support, we are creating a new European dynamic, offering foreign winners the chance to pitch to top French managers. This strengthens innovation ecosystems and helps young companies establish themselves in France. Veolia's support fosters entrepreneurship across borders, and together we are giving start-ups the means to accelerate their development and increase their European impact."

Anne Le Guennec, Senior Executive VP for Worldwide Water Technologies at Veolia, commented: "The Graines de Boss contest perfectly aligns with Veolia's mission to accelerate ecological transformation, and we are thrilled to sponsor its expansion to Belgium and Spain. By supporting this fertile ecosystem of innovation, we gain valuable insights into emerging solutions that address challenges in water, waste and energy management. It is time to GreenUp, and we are committed to helping start-ups with innovative ideas to scale up and speed up their development, transforming passionate concepts into impactful realities. I encourage all aspiring entrepreneurs to seize this opportunity and apply for the contest - your innovation could be the next game-changer in creating a more sustainable future for all."

For more details and to apply for the Graines de Boss competition:

ABOUT GRAINES DE BOSS

For over two decades, Graines de Boss has been a catalyst for innovation and growth in the French start-up ecosystem. With a network of over 1,500 mentors, including business leaders and executives from diverse sectors and companies of all sizes, the competition has made a significant impact. Since its inception in 2004, Graines de Boss has produced 228 laureates, boasting an impressive 80% business survival rate after three years. Moreover, it has facilitated over 850 million euros in investments for winning companies, cementing its position as a powerhouse in open innovation and start-up discovery for major corporations and investors alike. www.grainesdeboss.com

ABOUT VEOLIA

Veolia's ambition is to become the benchmark company for ecological transformation. With nearly 218,000 employees on five continents, the Group designs and deploys useful, practical solutions for managing water, waste and energy that help to radically change the world. Through its three complementary activities, Veolia contributes to developing access to resources, preserving available resources and renewing them. In 2023, the Veolia group served 113 million people with drinking water and 103 million with wastewater services, produced 42 terawatt-hours of energy and recovered 63 million metric tons of waste. Veolia Environnement (Paris Euronext: VIE) generated consolidated sales of €45.3 billion in 2023. www.veolia.com

CONTACTS

Graines de Boss
Fabrice Delon
Tel.+33 6 08 71 90 62
f.delon@grainesdeboss.com

Veolia Water Technologies
Belgium: Han Engelen
Tel.+32 473 521 403
han.engelen@veolia.com

Spain: Maria J. Fernandez
Tel.+34 630 88 66 73
mariaj.fernandez@veolia.com

Les technologies de Veolia sont prêtes à transformer les eaux usées en ressources dans une brasserie belge historique

rylee.lay@veolia.com — Thu, 20 Feb 2025 17:40:47 +0000

Veolia's technologies set to transform wastewater into resources at historic Belgian brewery rylee.lay@veolia.com Thu, 02/20/2025 - 12:40

February 20, 2025

Europe

This project emphasizes sustainable resource management, applying circular economy principles to optimize biogas valorization and water reuse, which are an integral part of Veolia's GreenUp strategic plan.
Advanced Veolia proprietary technologies will enable 70% water reuse, saving a volume of freshwater equivalent to the annual consumption of close to 3,000 Belgian residents.
The high-quality biogas produced represents a green source of renewable energy used to heat water processes and buildings, creating a sustainable energy recovery cycle that annually prevents the emission of 548 tons of CO2.

Veolia Water Technologies has been chosen by the Omer Vander Ghinste Brewery for the expansion of the wastewater treatment plant (WWTP) at its historic brewery close to Kortrijk, Belgium. Since 1892, Brewery Omer Vander Ghinste has been a fixture in Belgian brewing. The brewery is now focusing on sustainable growth, balancing expansion with responsible practices.

Veolia's extension of the WWTP is designed to support the brewery's growing operational needs while significantly reducing its environmental footprint. The comprehensive upgrade incorporates advanced technologies, including a ZeeWeed™ 500 membrane bioreactor system, anaerobic Biobed® Advanced EGSB and CaptuRO™, a high-recovery reverse osmosis system.

The bio-factory concept, where wastewater is transformed into valuable resources, is at the heart of this project. Veolia's EGSB technology plays a pivotal role in producing high-quality biogas from wastewater. This green source of renewable energy is subsequently processed and used to heat water and buildings, creating a sustainable energy recovery cycle that annually prevents the emission of 548 tons of CO2.

Furthermore, the advanced CaptuRO technology ensures that 70% of the water used in the brewing process is efficiently and securely recycled and reused for cooling water, bottle washing and cleaning of vessels, saving a volume of freshwater equivalent to the annual consumption of close to 3,000 Belgian residents. This approach not only minimizes waste but also exemplifies Veolia's vision for a circular economy in the industrial sector.

Anne Le Guennec, Senior Executive VP for Worldwide Water Technologies at Veolia, commented: "We are very proud to collaborate with the historic Omer Vander Ghinste brewery on this project that perfectly illustrates how our advanced technologies can improve both the sustainability and efficiency of an industrial site. By allowing 70% of water reuse and creating a renewable energy cycle, we demonstrate that ecological innovation can go hand in hand with operational efficiency, in connection with our GreenUp strategic plan."

ABOUT VEOLIA

Veolia Group aims to become the benchmark company for ecological transformation. Present on five continents with nearly 218,000 employees, the Group designs and deploys useful, practical solutions for the management of water, waste and energy that are contributing to a radical turnaround of the current situation. Through its three complementary activities, Veolia helps to develop access to resources, to preserve available resources and to renew them. In 2023, the Veolia group provided 113 million inhabitants with drinking water and 103 million with sanitation, produced 42 million megawatt hours of energy and treated 63 million tonnes of waste. Veolia Environment (Paris Euronext: VIE) achieved consolidated revenue of 45,351 million euros in 2023. www.veolia.com

Transition Industries et Veolia s’associent pour redéfinir l’utilisation de l'eau industrielle dans le cadre du projet Pacifico Mexinol au Mexique

rylee.lay@veolia.com — Mon, 13 Jan 2025 14:12:02 +0000

Transition Industries and Veolia partner to redefine industrial water use at the Pacifico Mexinol Project in Mexico rylee.lay@veolia.com Mon, 01/13/2025 - 09:12

January 13, 2025

Latin America

Pacifico Mexinol is a net-zero world scale methanol project that will produce 6,145 metric tons of methanol per day, a versatile chemical that serves as a building block for countless everyday products.
The site is set to become one of the world's largest applications of industrial water reuse from municipal effluent, leveraging Veolia's state-of-the-art technological solutions.

Transition Industries LLC, a developer of world-scale, net-zero carbon emissions methanol and hydrogen projects, and Veolia Water Technologies & Solutions, world leader in water technology, have signed an agreement to explore the provision of advanced industrial water technology for the Pacifico Mexinol project in Sinaloa, Mexico. Expected to initiate operations in 2028, Pacifico Mexinol is poised to be the world's largest standalone ultra-low carbon chemical production facility in the world, with an output of 6,145 metric tons (MT) per day.

The memorandum of understanding (MOU) outlines the collaboration between Transition Industries and Veolia to develop a purpose-driven water strategy for the Pacifico Mexinol project. Designed with Ahome Municipality's Drinking Water and Sewage Board (JAPAMA), this strategy would make the Pacifico Mexinol site one of the world's largest applications of industrial water reuse from municipal effluent, leveraging Veolia's state-of-the-art technological solutions.

The Pacifico Mexinol project's water management approach tackles water scarcity head-on by using innovative technologies to avoid tapping into freshwater sources, thereby preserving these precious resources for local agriculture and community needs.

Instead, it employs a closed-loop system that treats and recycles municipal wastewater, adhering to national regulations. This approach will prevent more than 8.5 million cubic meters of wastewater annually from being discharged into the Bay of Ohuira, significantly reducing environmental impact.

Under the terms of the MOU, Veolia would design and equip the water treatment plant with advanced technologies such as ZeeWeed 500D™ ultrafiltration membranes, PROflex™ reverse osmosis membranes and E-Cell™ electrodeionization. Veolia would also be responsible for commissioning and starting-up the equipment and technology to optimize the performance of the Pacifico Mexinol project treatment plant.

Balmore Brito, Pacifico-Mexinol Project Director and Head of Engineering and Technology for Transition Industries, said: "Years of community and municipal engagement have led to the development of a set of purpose-driven design solutions, like our wastewater strategy. The ability to partner with Veolia, a global leader in water solutions, to leverage technology and minimize negative environmental impacts, is foundational to our core values of combating climate change and leading in environmental and social responsibility."

Anne Le Guennec, Senior Executive VP for Worldwide Water Technologies at Veolia added: "We are very proud to partner with Transition Industries on this transformative project. Our best-in-class water technologies and regeneration processes will enable sustainable methanol production, contributing to the acceleration of decarbonization and reduction of greenhouse gas emissions, in full alignment with our GreenUP strategic program commitments."

Transition Industries is jointly developing Pacifico Mexinol with the International Finance Corporation (IFC), a member of the World Bank Group. When it initiates operations in 2028, Pacifico Mexinol is expected to be the largest single ultra-low carbon methanol facility in the world - producing approximately 350,000 MT of green methanol and 1.8 million MT of blue methanol annually from natural gas with carbon capture.

This partnership between Transition Industries and Veolia marks a significant step forward in sustainable industrial practices, demonstrating the power of collaboration in addressing global environmental challenges while driving economic growth.

ABOUT TRANSITION INDUSTRIES

Transition Industries LLC, based in Houston, Texas, is a developer of world-scale, net-zero carbon emissions methanol and hydrogen projects in North America to address climate change and promote environmental and social sustainability. For additional information about Pacifico Mexinol or Transition Industries, email inquiries@transitionind.com.

ABOUT VEOLIA

CONTACTS

VEOLIA WATER TECH LATAM
Diego Fuentes
Tel.+55 (11) 971 36 57 52
diego.fuentes1@veolia.com

VEOLIA WATER TECH GLOBAL MEDIA RELATIONS
Manon Painchaud
Tel.+1 418 573 2735
manon.painchaud@veolia.com